Exploring how chronic pain affects the risk of opioid misuse using brain imaging

Understanding pain embodiment and opioid misuse risk in chronic pain using neuroimaging

NIH-funded research University of Utah · NIH-11165238

This study is looking at how people with chronic pain think about their pain and how that might affect their risk of misusing opioids, using brain scans to compare healthy people, those with chronic pain, and those who have recovered from it, all to help find better ways to treat pain and prevent opioid problems.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11165238 on NIH RePORTER

What this research studies

This research investigates the relationship between chronic pain and the risk of opioid misuse by examining how individuals perceive their pain through a concept called pain embodiment. Using advanced brain imaging techniques, the study will compare healthy individuals, those with chronic pain, and individuals who have recovered from chronic pain. The goal is to understand how the brain processes pain and how this may influence behaviors related to opioid use. By identifying these connections, the research aims to inform better treatment strategies for managing chronic pain and reducing opioid dependency.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from chronic pain, as well as those who have recovered from chronic pain.

Not a fit: Patients who do not experience chronic pain or have not been affected by opioid misuse may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies that reduce the reliance on opioids and lower the risk of misuse.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between pain perception and substance use, suggesting that this approach could yield valuable insights.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.