Exploring how chlamydia may increase the risk of cervical cancer linked to HPV infections
Official title: Investigating whether chlamydia trachomatis can increase the infectivity of HPV during genital tract infections
Funded at Marian University · NIH-10807056 · Data updated 2026-11-12
This study is looking at how infections with Chlamydia and HPV might work together to increase the risk of cervical cancer, and it aims to find out how this happens so that we can improve ways to prevent and treat the disease.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marian University NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | March 10, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $168,753 |
| NIH project number | 5R21AI175847-02 |
| Project ID | NIH-10807056 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have been diagnosed with HPV and/or Chlamydia infections.
✕Less likely to help
Patients who do not have HPV or Chlamydia infections are unlikely to benefit from this research.
What this research studies
This research investigates the relationship between Chlamydia trachomatis infections and the increased risk of cervical cancer associated with human papillomavirus (HPV). It aims to understand how co-infections with these pathogens may enhance the immune response and contribute to cancer development. By examining the cellular interactions and immune responses in the genital tract, the study seeks to identify potential biological factors that could serve as co-factors in the oncogenesis process. Patients may benefit from insights that could lead to improved prevention and treatment strategies for cervical cancer.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cervical cancer in women with HPV and Chlamydia infections.
How similar studies have gone: Previous research has indicated a potential link between Chlamydia infections and increased cervical cancer risk, suggesting that this investigation builds on established findings.
Where this research is happening
-
Marian University
Indianapolis, United States Active
Researchers
- Principal investigator: Derbigny, Wilbert a — Marian University
- Study coordinator: Derbigny, Wilbert a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.