Exploring how certain sulfur compounds can protect the heart
Official title: Probing the cardioprotective effects of sulfane sulfurs with next generation fluorescent sensors
Funded at Brown University · NIH-10925233 · Data updated 2026-11-12
This study is looking at how certain sulfur compounds can help protect heart cells during heart attacks and heart failure, and it's for anyone interested in new ways to better understand and treat heart conditions.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31HL170516-02 |
| Project ID | NIH-10925233 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cardiovascular diseases, particularly those experiencing myocardial ischemia-reperfusion injury or heart failure.
✕Less likely to help
Patients with non-cardiovascular conditions or those who do not have any heart-related issues may not benefit from this research.
What this research studies
This research investigates the protective effects of sulfane sulfurs on heart cells, particularly in conditions like heart attacks and heart failure. By developing advanced fluorescent sensors, the study aims to visualize and understand how these sulfur compounds function within cardiac cells. The goal is to create tools that can help identify and measure these compounds in the body, potentially leading to new diagnostic methods and treatments for cardiovascular diseases. Patients may benefit from improved understanding and management of heart conditions through these innovative approaches.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and therapies for cardiovascular diseases, improving patient outcomes.
How similar studies have gone: While the specific approach of using sulfane sulfurs in this context is novel, related research has shown promise in understanding sulfur compounds' roles in cardiovascular health.
Where this research is happening
-
Brown University
Providence, United States Active
Researchers
- Principal investigator: Shieh, Meg — Brown University
- Study coordinator: Shieh, Meg
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.