Exploring how certain natural compounds are made for potential medical and agricultural uses
Official title: Investigating labdane-related diterpenoid biosynthesis
Funded at Iowa State University · NIH-11011913 · Data updated 2026-11-12
This study is looking at how certain natural compounds, which could help create new medicines and improve farming practices, are made in plants, and it aims to find ways to make these compounds more effective for people who need better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa State University NIH-funded |
| Lab location | 1 site (Ames, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $401,595 |
| NIH project number | 1R35GM156300-01 |
| Project ID | NIH-11011913 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals interested in novel antibiotic treatments or those affected by agricultural chemical exposure.
✕Less likely to help
Patients who are not interested in agricultural applications or who do not have conditions related to antibiotic resistance may not receive benefits from this research.
What this research studies
This research investigates the biosynthesis of labdane-related diterpenoids (LRDs), a class of natural compounds that have significant pharmaceutical and agricultural applications. By studying the enzymes involved in the production of these compounds, the research aims to enhance our understanding of their biological activity and potential uses. The approach includes engineering the biosynthetic pathways to improve the yield and effectiveness of these compounds, which could lead to new antibiotics and safer agricultural practices. Patients may benefit from the development of novel medications derived from these natural products.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics and safer agricultural practices that improve health outcomes.
How similar studies have gone: Previous research has shown promise in utilizing natural products for medical applications, indicating that this approach has potential for success.
Where this research is happening
-
Iowa State University
Ames, United States Active
Researchers
- Principal investigator: Peters, Reuben John — Iowa State University
- Study coordinator: Peters, Reuben John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.