Exploring how certain brain circuits influence learning and behavior
Determining the role of amygdalostriatal transition zone circuits in associative learning and motivated behaviors
This study is looking at how certain parts of the brain help us learn connections between things and the actions we take, especially in people dealing with anxiety and depression, to find better ways to help them feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11052629 on NIH RePORTER |
What this research studies
This research investigates the role of specific brain circuits, particularly the amygdalostriatal transition zone, in how we learn associations between stimuli and the behaviors they trigger. By using advanced techniques like optogenetics and in vivo electrophysiology, the study aims to identify how these circuits function and how they may be altered in conditions like anxiety and depression. The goal is to understand the neural mechanisms behind motivated behaviors and learning, which could lead to better treatments for related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety, depression, or PTSD who may benefit from new treatment approaches.
Not a fit: Patients with neurological disorders unrelated to anxiety, depression, or associative learning may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for anxiety, depression, and PTSD by targeting the neural circuits involved in associative learning.
How similar studies have performed: Other research has shown promising results in understanding brain circuits related to learning and behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Mills, Fergil — University of Utah
- Study coordinator: Mills, Fergil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.