Exploring how certain brain cells develop and function
Understanding the developmental progression of subpallial neural progenitor cells
This study is looking at how certain brain cells develop, which is important for understanding conditions like autism and schizophrenia, and it aims to find ways to improve treatments for these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-10880563 on NIH RePORTER |
What this research studies
This research investigates the developmental progression of subpallial neural progenitor cells, which are crucial for forming various brain structures involved in higher brain functions. By studying these cells, the research aims to uncover the cellular and molecular mechanisms that guide their development, particularly in relation to neuropsychiatric disorders like autism and schizophrenia. The approach includes using advanced genetic techniques in mouse models to understand how these progenitor cells differentiate into various types of neurons and glial cells. This knowledge could lead to improved treatments for conditions that affect brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism or related neuropsychiatric disorders.
Not a fit: Patients with neuropsychiatric disorders not related to the development of subpallial neural progenitor cells may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and therapies for neuropsychiatric disorders, potentially improving outcomes for affected individuals.
How similar studies have performed: While research on neural progenitor cells has been conducted, this specific focus on subpallial NPCs is relatively novel and has not been extensively studied.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Cao, Xinwei — St. Jude Children's Research Hospital
- Study coordinator: Cao, Xinwei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.