Exploring how cellular responses to drugs can inform disease understanding and treatment.
The LINCS DCIC Engagement Plan with the CFDE
This study is looking at how changes in human cells, caused by different drugs and genetic tweaks, can help us understand diseases better and find new ways to use existing medications, which could lead to more personalized and effective treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11089689 on NIH RePORTER |
What this research studies
This research focuses on utilizing a vast collection of data from human cells that have been altered by various small molecules and genetic modifications. By analyzing these cellular responses through advanced techniques like transcriptomics and proteomics, the project aims to uncover the underlying mechanisms of diseases and identify potential new uses for existing drugs. Patients may benefit from insights gained about how different treatments affect cellular behavior, which could lead to more effective therapies tailored to individual conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that could be addressed through drug repurposing or those interested in understanding the molecular mechanisms of their diseases.
Not a fit: Patients with conditions that are not related to the cellular responses being studied may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved drug repurposing and personalized treatment strategies for various diseases.
How similar studies have performed: Previous research utilizing large-scale cellular data has shown promise in identifying new therapeutic targets and drug repurposing opportunities.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Ma'ayan, Avi — Icahn School of Medicine at Mount Sinai
- Study coordinator: Ma'ayan, Avi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.