Exploring how cells move in three-dimensional environments
Understanding the control mechanisms of 3D cell migration from new dimensions
['FUNDING_OTHER'] · OREGON STATE UNIVERSITY · NIH-10832542
This study is looking at how cells move in 3D spaces, which is important for understanding how our bodies work and how diseases like cancer spread, using special imaging and computer techniques to see how cells behave in different environments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON STATE UNIVERSITY (nih funded) |
| Locations | 1 site (CORVALLIS, UNITED STATES) |
| Trial ID | NIH-10832542 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that control how cells migrate in three-dimensional tissue spaces, which is crucial for understanding human biology and diseases like cancer. The approach involves using advanced imaging techniques and deep learning to track cell movement and analyze the effects of the surrounding extracellular matrix on cell behavior. By studying how cells transition between different migration modes, the research aims to uncover the intrinsic and extrinsic factors that influence these processes, ultimately contributing to advancements in tissue engineering and cancer therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or conditions that involve abnormal cell migration and tissue remodeling.
Not a fit: Patients with stable, non-migratory conditions or those not affected by cancer or tissue engineering challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for manipulating cell movement, which may enhance cancer treatment and tissue regeneration.
How similar studies have performed: Other research has shown promising results in understanding cell migration in two-dimensional environments, but this approach to three-dimensional migration is relatively novel.
Where this research is happening
CORVALLIS, UNITED STATES
- OREGON STATE UNIVERSITY — CORVALLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUN, BO — OREGON STATE UNIVERSITY
- Study coordinator: SUN, BO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer