Exploring how cells communicate using newly discovered signaling pathways
Investigation of a Newly Discovered Organelle-Based Signaling Paradigm
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10842110
This study looks at how the structure of cells affects how they talk to each other and respond to outside signals, especially focusing on hidden parts inside the cell that might help certain medications work better, which could lead to new ways to treat diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10842110 on ClinicalTrials.gov |
What this research studies
This research investigates how the architecture of cells influences their ability to communicate and respond to signals from outside the cell. It challenges the traditional view that receptors on the cell surface are the only sites for signal action, revealing that internal compartments like endosomes and Golgi membranes also play crucial roles. By developing innovative tools to visualize these processes, the research aims to uncover how certain drugs may work by accessing these internal sites, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Patients with conditions related to cell signaling dysfunction, such as endocrine disorders or certain cancers, may benefit from this research.
Not a fit: Patients with conditions unrelated to cell signaling or those who do not respond to current pharmacological treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments by identifying new ways drugs can interact with cells.
How similar studies have performed: Previous research has shown promising results in understanding cell signaling through similar innovative approaches, suggesting potential for success in this area.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IRANNEJAD, ROSHANAK — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: IRANNEJAD, ROSHANAK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.