Exploring how cells communicate and process information in complex environments
Official title: Understanding robust cellular information processing in complex environments and development of enabling single-cell analysis technologies
Funded at University of Chicago · NIH-11037914 · Data updated 2026-11-12
This study is looking at how our immune cells respond to different signals in the environment, which can help us understand and improve treatments for infections, autoimmune diseases, and cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | March 1, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $622,812 |
| NIH project number | 5R35GM148231-03 |
| Project ID | NIH-11037914 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with autoimmune conditions or cancers who are interested in how their immune responses are regulated.
✕Less likely to help
Patients with stable, non-immune related conditions may not receive direct benefits from this research.
What this research studies
This research investigates how cells encode and communicate signals in response to various environmental stimuli, which is crucial for understanding conditions like infections, autoimmunity, and cancer. By utilizing advanced technologies for high-throughput single-cell analysis, the research aims to uncover the mechanisms behind cytokine production and variability in cellular responses. Patients may benefit from insights gained about how immune cells react to different signals, potentially leading to improved treatments for autoimmune diseases and cancers.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for autoimmune diseases and cancers.
How similar studies have gone: Other research has shown success in understanding cellular signaling and immune responses, making this approach promising yet still innovative.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Tay, Savas — University of Chicago
- Study coordinator: Tay, Savas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.