Exploring how cannabis compounds can reduce pain and inflammation.
Modulation of pain mechanisms by cannabis-derived phytochemicals.
['FUNDING_R01'] · QUEEN'S MEDICAL CENTER · NIH-10990524
This study is looking at how certain compounds from cannabis might help reduce pain and inflammation for people with chronic pain from conditions like injuries, nerve issues, cancer, or autoimmune diseases, offering a potential alternative to opioids for pain relief.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | QUEEN'S MEDICAL CENTER (nih funded) |
| Locations | 1 site (HONOLULU, UNITED STATES) |
| Trial ID | NIH-10990524 on ClinicalTrials.gov |
What this research studies
This research investigates the potential of cannabis-derived phytochemicals to modulate pain mechanisms, particularly in patients suffering from chronic pain due to conditions like musculoskeletal injuries, neurological disorders, cancer, or autoimmune diseases. The study employs a combination of molecular and cellular signaling techniques to understand how specific cannabinoids can inhibit calcium signaling in immune cells, which may lead to reduced inflammation and pain. By identifying and characterizing the anti-inflammatory properties of these compounds, the research aims to provide alternative pain management strategies that could lessen reliance on opioids.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing chronic pain from various conditions, such as musculoskeletal injuries, cancer, or autoimmune disorders.
Not a fit: Patients who do not suffer from chronic pain or have conditions unrelated to inflammation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer new, effective pain relief options for patients suffering from chronic pain without the risks associated with opioid use.
How similar studies have performed: Previous research has shown promising results in using cannabinoids for pain management, indicating that this approach has potential based on existing evidence.
Where this research is happening
HONOLULU, UNITED STATES
- QUEEN'S MEDICAL CENTER — HONOLULU, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SETO, TODD B — QUEEN'S MEDICAL CENTER
- Study coordinator: SETO, TODD B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.