Exploring how cannabinoids and opioids interact in pain management
Opioid and cannabinoid interactions in pain and reward
This study is looking at how combining cannabinoids like CBD with opioids like oxycodone can help people with chronic pain feel better while also lowering the chances of becoming dependent on opioids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10886999 on NIH RePORTER |
What this research studies
This research investigates the interactions between cannabinoids, like CBD, and opioids, such as oxycodone, in managing chronic pain. It aims to understand how these substances can work together to enhance pain relief while reducing the risk of opioid dependence. The study employs advanced techniques, including behavioral assessments and neuroimaging, to evaluate the effectiveness and safety of these combined treatments. By focusing on the mechanisms of pain and reward, the research seeks to develop better pain management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic pain who may benefit from alternative pain management strategies.
Not a fit: Patients who do not experience chronic pain or those who are not interested in cannabinoid or opioid treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management options for patients suffering from chronic pain.
How similar studies have performed: Previous research has shown promising results in the use of cannabinoids for pain relief, suggesting that this approach may yield beneficial outcomes.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Neubert, John K — University of Florida
- Study coordinator: Neubert, John K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.