Exploring how brain stimulation affects navigation and memory in people with epilepsy
Neurostimulation and Recording of Real World Spatial Navigation in Humans
['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10892065
This study is looking at how people with epilepsy navigate and remember places while their brain activity is monitored, using fun tools like virtual and augmented reality, to help us learn more about how their brains work.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10892065 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between spatial navigation, memory, and brain activity in individuals with epilepsy who have a special device implanted in their brains. By using advanced technologies like virtual reality and augmented reality, researchers will monitor brain activity while participants navigate different environments. The study aims to understand how specific brain patterns influence navigation and memory, providing insights into cognitive functions. Participants will be engaged in real-world tasks while their brain activity is recorded, allowing for a comprehensive analysis of their cognitive processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with epilepsy who have been implanted with the Neuropace Responsive Neurostimulator (RNS®).
Not a fit: Patients without epilepsy or those who do not have the RNS device may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for cognitive impairments associated with epilepsy and related conditions.
How similar studies have performed: While the approach of using deep brain stimulation and recording during navigation tasks is innovative, similar methodologies have shown promise in understanding brain functions in other contexts.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUTHANA, NANTHIA A — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: SUTHANA, NANTHIA A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease