Exploring how brain stimulation affects cannabis use in heavy users

Imaging the Effects of Intermittent Thetaburst Stimulation on Cannabis Self-Administration in Heavy Cannabis Users

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10667460

This study is looking at how a special brain stimulation technique can help people who struggle with cannabis use by reducing their cravings and making it easier for them to control their use.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10667460 on NIH RePORTER

What this research studies

This research investigates the effects of intermittent theta burst stimulation (iTBS) on the brain's ability to manage cravings and reduce cannabis self-administration in individuals with cannabis use disorder. By applying this non-invasive brain stimulation technique to the dorsolateral prefrontal cortex, the study aims to enhance cognitive control and decrease the neural response to cannabis-related cues. Participants will undergo brain imaging to assess changes in brain activity associated with their cannabis use. The ultimate goal is to identify effective interventions for reducing cannabis consumption and preventing relapse.

Who could benefit from this research

Good fit: Ideal candidates for this research are heavy cannabis users who may be experiencing difficulties in controlling their cannabis consumption.

Not a fit: Patients who do not use cannabis or have mild cannabis use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatment options for individuals struggling with cannabis use disorder.

How similar studies have performed: Previous research has shown promise in using brain stimulation techniques to modify drug cue responses, indicating potential for success in this approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.