Exploring how brain regions communicate to control behavior
Understanding the Neural Mechanisms Controlling Brain-wide Dynamics
['FUNDING_R01'] · PRINCETON UNIVERSITY · NIH-11002297
This study is looking at how different parts of the brain communicate with each other to help us understand behaviors, especially in mice, and it hopes to find ways to improve behaviors in people with conditions like autism and schizophrenia.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-11002297 on ClinicalTrials.gov |
What this research studies
This research investigates the neural mechanisms that govern how information flows between different regions of the brain, which is crucial for understanding behaviors. By using advanced techniques like mesoscale calcium imaging, the study aims to identify specific patterns of neural activity associated with various behaviors in mice. The findings could shed light on how disruptions in these processes may contribute to conditions like autism spectrum disorder and schizophrenia. Ultimately, the research seeks to quantify and manipulate these neural dynamics to better understand and potentially improve behavioral outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder or related neuropsychiatric conditions.
Not a fit: Patients with conditions unrelated to neuropsychiatric disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and interventions for neuropsychiatric disorders, particularly autism spectrum disorder.
How similar studies have performed: Other research has shown promise in understanding neural dynamics and their relation to behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUSCHMAN, TIMOTHY J. — PRINCETON UNIVERSITY
- Study coordinator: BUSCHMAN, TIMOTHY J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder