Exploring how brain cell types relate to opioid addiction
Uncovering links between neuronal transcriptomic and functional profiles in opioid addiction
This study is looking at how different brain cells are involved in opioid addiction by observing mice and their behavior with opioids, which could help us find new ways to treat substance use disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10982915 on NIH RePORTER |
What this research studies
This research investigates the complex relationship between different types of brain cells and their roles in opioid addiction. By using advanced techniques like optogenetics and electrophysiology, researchers will study how specific neuronal subtypes behave during opioid self-administration in mice. The project aims to link these cell types to their genetic profiles, which can only be analyzed in post-mortem brain tissue. This approach may lead to new insights into substance use disorders and potential therapeutic targets for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with opioid addiction or those at risk of developing substance use disorders.
Not a fit: Patients who do not have a history of opioid use or addiction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for opioid addiction by identifying specific brain cell types and their functions.
How similar studies have performed: While this research employs novel techniques, similar approaches in understanding brain function and addiction have shown promise in other studies.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Sjulson, Lucas L — Albert Einstein College of Medicine
- Study coordinator: Sjulson, Lucas L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.