Exploring how brain activity and real-life experiences relate to feelings of paranoia in psychosis.
Using Multimodal Neuroimaging and Real-World Experience Sampling to Understand Negative Affect and Paranoid Ideation in Psychosis
['FUNDING_R01'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-10830340
This study is looking at how brain activity relates to paranoid thoughts in people with conditions like schizophrenia, and it’s for anyone who experiences paranoia or knows someone who does, to help find better ways to treat these feelings.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MARYLAND, COLLEGE PARK (nih funded) |
| Locations | 1 site (COLLEGE PARK, UNITED STATES) |
| Trial ID | NIH-10830340 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between brain activity and paranoid thoughts in individuals with psychosis, such as schizophrenia. By using advanced neuroimaging techniques and smartphone surveys, the study aims to identify the brain circuits involved in anxiety and how everyday social cues can trigger paranoia. Participants will include both individuals experiencing paranoia and those without such experiences, allowing for a comprehensive understanding of the condition. The goal is to translate these findings into potential therapeutic strategies that can improve treatment outcomes for patients.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals diagnosed with schizophrenia or other psychotic disorders who experience paranoid thoughts.
Not a fit: Patients who do not experience paranoia or have other unrelated mental health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for paranoia and related symptoms in psychosis.
How similar studies have performed: Previous research has shown promise in using neuroimaging and real-world data to understand mental health conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
COLLEGE PARK, UNITED STATES
- UNIV OF MARYLAND, COLLEGE PARK — COLLEGE PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BLANCHARD, JACK J. — UNIV OF MARYLAND, COLLEGE PARK
- Study coordinator: BLANCHARD, JACK J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder