Exploring how body clocks and fat metabolism are connected
Unraveling the molecular interconnections between circadian rhythms and lipid metabolism
This study is looking at how our body's natural daily rhythms affect how we process fats, and it’s for anyone interested in understanding how disruptions in these rhythms might lead to health issues related to metabolism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-St. Louis NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11011603 on NIH RePORTER |
What this research studies
This research investigates the relationship between circadian rhythms, which are the body's natural 24-hour cycles, and lipid metabolism, the process by which fats are broken down and utilized. It aims to understand how disruptions in these rhythms can lead to metabolic disorders and how lipid molecules, particularly phosphatidic acid, influence the functioning of the circadian clock. By studying these interactions, the research seeks to uncover the molecular mechanisms that link metabolism and circadian functions, potentially leading to new insights into metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing metabolic disorders or those with conditions influenced by circadian rhythm disruptions.
Not a fit: Patients without metabolic disorders or those whose conditions are unrelated to circadian rhythms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing metabolic disorders by targeting the interplay between circadian rhythms and lipid metabolism.
How similar studies have performed: While the specific interactions being studied are novel, previous research has shown promising results in understanding the links between circadian rhythms and metabolism.
Where this research is happening
Saint Louis, United States
- University of Missouri-St. Louis — Saint Louis, United States (Active)
Researchers
- Principal investigator: Wang, Xuemin — University of Missouri-St. Louis
- Study coordinator: Wang, Xuemin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.