Exploring how blood vessel health affects memory and thinking in Alzheimer's disease.
Vascular Contributions to Cognitive Impairment and Dementia (VCID)
This study is looking at how problems with blood vessels might affect memory and thinking skills in people with Alzheimer's and similar conditions, and it's for anyone interested in understanding more about these issues and helping future scientists learn about them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-11074720 on NIH RePORTER |
What this research studies
This research investigates the role of vascular factors in cognitive decline and dementia, particularly in Alzheimer's disease and related dementias. It aims to understand how issues like small vessel disease and blood-brain barrier dysfunction contribute to these conditions. The approach includes genetic and biomarker studies in both humans and model organisms, utilizing advanced multi-omic technologies. A key component of this research is a specialized conference designed to train the next generation of scientists in this emerging field.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing cognitive decline or diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with cognitive impairments not related to vascular issues or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with Alzheimer's disease and related dementias.
How similar studies have performed: Other research has shown promising results in understanding the vascular contributions to cognitive decline, indicating that this area is gaining traction in the scientific community.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Howell, Gareth R — Jackson Laboratory
- Study coordinator: Howell, Gareth R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.