Exploring how blood vessel health affects Alzheimer's disease
Mid-Career Program for Vascular Contributions to Alzheimer's disease
This study is looking at how problems with blood vessels might affect memory and thinking as we age, especially in people with Alzheimer's, and it also aims to train new researchers to find ways to improve blood flow and brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10890181 on NIH RePORTER |
What this research studies
This research focuses on understanding how vascular health impacts cognitive aging and Alzheimer's disease. It aims to investigate the mechanisms by which blood vessel dysfunction may contribute to cognitive decline and dementia. The program will also train new researchers, particularly those from underrepresented backgrounds, to explore potential therapies, such as angiotensin receptor blockers, that could improve vascular health and cognitive outcomes. By examining the links between cardiovascular disease and Alzheimer's, the research seeks to uncover new treatment avenues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with cardiovascular risk factors like hypertension or diabetes.
Not a fit: Patients who do not have any vascular risk factors or cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve cognitive health and slow the progression of Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in exploring the relationship between vascular health and cognitive decline, indicating that this approach has potential for success.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Hajjar, Ihab M — Ut Southwestern Medical Center
- Study coordinator: Hajjar, Ihab M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.