Exploring how biological clocks affect health and disease

Chemical Biology Approaches for Studying Circadian Rhythms

['FUNDING_OTHER'] · UNIVERSITY OF MASSACHUSETTS AMHERST · NIH-11083102

This study is looking at how our body's natural clock affects diseases like cancer and heart disease, and it aims to find new ways to understand and possibly improve treatments for these conditions by exploring how disruptions in our daily rhythms can impact our health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MASSACHUSETTS AMHERST (nih funded)
Locations1 site (HADLEY, UNITED STATES)
Trial IDNIH-11083102 on ClinicalTrials.gov

What this research studies

This research investigates the role of circadian rhythms, which are the body's internal timekeeping systems, in various diseases such as cancer and heart disease. By developing innovative chemical biology tools, the project aims to study these rhythms at a molecular level, allowing for a better understanding of how disruptions in these rhythms can lead to health issues. The approach includes creating new methods to visualize and target proteins involved in circadian processes, which could reveal important insights into their functions and interactions. Patients may benefit from findings that could lead to new treatments or preventive strategies for diseases linked to circadian rhythm disruptions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from conditions like cancer, heart disease, or metabolic disorders that may be influenced by circadian rhythms.

Not a fit: Patients with conditions unrelated to circadian rhythms or those who do not experience disruptions in their biological clocks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for managing diseases associated with circadian rhythm disruptions.

How similar studies have performed: Previous research has shown promising results in understanding circadian rhythms and their impact on health, indicating that this approach could yield valuable insights.

Where this research is happening

HADLEY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers, Cardiac Diseases, Cardiac Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.