Exploring how biological and lifestyle factors affect Alzheimer's disease in Black women.
Understanding Biological and Lifestyle Contributions to Alzheimer's Disease Pathology and Clinical Profiles in Black Women: Defining Prevention Targets in High Risk Groups
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11249047
This study is looking at how things like inflammation and physical activity affect memory and brain health in older Black women at risk for Alzheimer's disease, with the goal of finding ways to help prevent or slow down cognitive decline.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11249047 on ClinicalTrials.gov |
What this research studies
This research investigates the unique contributions of biological and lifestyle factors to Alzheimer's disease (AD) pathology and clinical profiles specifically in older Black women. It aims to understand how inflammation and physical activity influence tau protein accumulation and cognitive decline in this high-risk group. By focusing on modifiable risk factors, the study seeks to identify potential prevention targets that could help delay or prevent cognitive decline. The research employs a combination of biological assessments and lifestyle evaluations to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for participation are older Black women who are at risk for Alzheimer's disease.
Not a fit: Patients who are not Black or who do not fall within the older age range may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted prevention strategies that significantly reduce the risk of Alzheimer's disease in Black women.
How similar studies have performed: Previous research has shown promising results in understanding the impact of lifestyle factors on Alzheimer's disease, but this specific focus on Black women is relatively novel.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BANKS, SARAH — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: BANKS, SARAH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome