Exploring how biological and lifestyle factors affect Alzheimer's disease in Black women.
Official title: Understanding Biological and Lifestyle Contributions to Alzheimer's Disease Pathology and Clinical Profiles in Black Women: Defining Prevention Targets in High Risk Groups
Funded at University of California, San Diego · NIH-11249047 · Data updated 2026-11-12
This study is looking at how things like inflammation and physical activity affect memory and brain health in older Black women at risk for Alzheimer's disease, with the goal of finding ways to help prevent or slow down cognitive decline.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | December 15, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $82,229 |
| NIH project number | 3R01AG077579-03S3 |
| Project ID | NIH-11249047 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are older Black women who are at risk for Alzheimer's disease.
✕Less likely to help
Patients who are not Black or who do not fall within the older age range may not receive benefit from this research.
What this research studies
This research investigates the unique contributions of biological and lifestyle factors to Alzheimer's disease (AD) pathology and clinical profiles specifically in older Black women. It aims to understand how inflammation and physical activity influence tau protein accumulation and cognitive decline in this high-risk group. By focusing on modifiable risk factors, the study seeks to identify potential prevention targets that could help delay or prevent cognitive decline. The research employs a combination of biological assessments and lifestyle evaluations to gather comprehensive data.
Why it matters
Potential benefit: If successful, this research could lead to targeted prevention strategies that significantly reduce the risk of Alzheimer's disease in Black women.
How similar studies have gone: Previous research has shown promising results in understanding the impact of lifestyle factors on Alzheimer's disease, but this specific focus on Black women is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Banks, Sarah — University of California, San Diego
- Study coordinator: Banks, Sarah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.