Exploring how biological and lifestyle factors affect Alzheimer's disease in Black women

Understanding Biological and Lifestyle Contributions to Alzheimer's Disease Pathology and Clinical Profiles in Black Women: Defining Prevention Targets in High Risk Groups

NIH-funded research University of California, San Diego · NIH-11221437

This study is looking at how things like inflammation and exercise affect Alzheimer's disease in Black women, with the goal of finding ways to help prevent or slow down memory loss.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11221437 on NIH RePORTER

What this research studies

This research investigates the unique contributions of biological and lifestyle factors to Alzheimer's disease (AD) pathology and clinical profiles specifically in Black women. It aims to understand how inflammation and physical activity influence tau protein accumulation and cognitive decline in this high-risk group. By focusing on modifiable risk factors, the study seeks to identify potential prevention targets that could delay or prevent cognitive decline. The research employs a combination of biological assessments and lifestyle evaluations to gather comprehensive data.

Who could benefit from this research

Good fit: Ideal candidates for this research are older Black women who are at risk for Alzheimer's disease.

Not a fit: Patients who are not Black or who do not fall within the older age range may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to targeted prevention strategies for Alzheimer's disease in Black women, improving their cognitive health outcomes.

How similar studies have performed: Other research has shown success in exploring the impact of lifestyle factors on Alzheimer's disease, but this specific focus on Black women is relatively novel.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.