Exploring how biological and lifestyle factors affect Alzheimer's disease in Black women.
Official title: Understanding Biological and Lifestyle Contributions to Alzheimer's Disease Pathology and Clinical Profiles in Black Women: Defining Prevention Targets in High Risk Groups
Funded at University of California, San Diego · NIH-10980511 · Data updated 2026-11-12
This study is looking at how things like inflammation and physical activity affect memory and thinking skills in older Black women with Alzheimer's disease, to find ways to help them stay sharp longer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | December 15, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $693,005 |
| NIH project number | 5R01AG077579-03 |
| Project ID | NIH-10980511 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older Black women who are at risk for Alzheimer's disease.
✕Less likely to help
Patients who are not Black or who do not fall within the older age range may not benefit from this research.
What this research studies
This research investigates the unique contributions of biological and lifestyle factors to Alzheimer's disease (AD) in older Black women, a group that has been historically underrepresented in AD research. The study focuses on how inflammation and physical activity may influence tau protein accumulation and cognitive decline. By examining these factors, the research aims to identify modifiable risk and protective elements that could help delay or prevent cognitive decline in this high-risk population. Participants will be involved in assessments that explore these relationships over the course of the study.
Why it matters
Potential benefit: If successful, this research could lead to targeted prevention strategies for Alzheimer's disease specifically tailored for Black women.
How similar studies have gone: Previous research has shown promising results in understanding the impact of lifestyle factors on Alzheimer's disease, but this specific focus on Black women is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Banks, Sarah — University of California, San Diego
- Study coordinator: Banks, Sarah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.