NIH-funded research R01 grant

Exploring how bilingualism affects cognitive health in Hispanics with language disorders

Official title: Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive Aphasia

Funded at University of Texas at Austin · NIH-11082935 · Data updated 2026-11-12

This study is looking at how being bilingual might help Hispanic individuals with primary progressive aphasia, a type of dementia that affects language, by exploring how their language skills and experiences can influence their brain's ability to stay strong against decline.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startDecember 1, 2022
Project endAugust 31, 2025
Funding year2024
Award (this year)$30,900
NIH project number3R01AG080470-02S1
Project IDNIH-11082935 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Hispanic individuals who are bilingual and have been diagnosed with primary progressive aphasia.

Less likely to help

Patients who are monolingual or do not have language-related dementia may not benefit from this research.

What this research studies

This research investigates the relationship between bilingualism and cognitive reserve in Hispanic individuals diagnosed with primary progressive aphasia (PPA), a type of dementia that primarily affects language abilities. The study aims to understand how factors such as language proficiency, use, and age of acquisition influence cognitive resilience in bilingual patients. By examining these aspects, the research seeks to clarify the mixed findings regarding bilingualism's protective effects against Alzheimer's disease and related disorders. Participants will be assessed through various cognitive and language evaluations to identify patterns of language decline and resilience.

Why it matters

Potential benefit: If successful, this research could provide insights into how bilingualism may help protect against cognitive decline in patients with Alzheimer's disease and related disorders.

How similar studies have gone: Previous research has shown promising results regarding the cognitive benefits of bilingualism, but this specific focus on PPA and bilingual factors is relatively novel.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Grasso, Stephanie M — University of Texas at Austin
  • Study coordinator: Grasso, Stephanie M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.