Exploring how ancestry affects oropharyngeal cancer biology and treatment outcomes.
Determining the impact of ancestry on oropharyngeal cancer biology and treatment response.
['FUNDING_R21'] · BAYLOR COLLEGE OF MEDICINE · NIH-10869860
This study is looking at how a person's background might affect the biology of oropharyngeal cancer, especially in African American patients, to understand why they often have worse treatment outcomes and to find ways to improve their care.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10869860 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between ancestry and the biology of oropharyngeal cancer (OPC), particularly focusing on African American patients who often experience poorer treatment outcomes. By analyzing clinical data and genomic information from two unique cohorts enriched with African American patients, the study aims to determine if differences in tumor biology contribute to these disparities. The research will assess how factors like tumor characteristics and the immune environment may influence treatment responses and survival rates. This approach seeks to provide a deeper understanding of the biological underpinnings of OPC in diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include African American patients diagnosed with oropharyngeal cancer.
Not a fit: Patients with oropharyngeal cancer who are not of African American descent may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for African American patients with oropharyngeal cancer.
How similar studies have performed: While research on cancer disparities exists, this specific investigation into the interplay between ancestry and OPC biology is novel and has not been extensively studied.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SANDULACHE, VLAD C — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: SANDULACHE, VLAD C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bladder Cancer, Cancer Biology, Cancer Patient, Cancer Treatment, Cancers