Exploring how ancestry affects lung adenocarcinoma
Official title: Understanding Ancestral Contribution to Lung Adenocarcinoma
Funded at Sloan-Kettering Inst Can Research · NIH-10892072 · Data updated 2026-11-12
This study is looking at how genetic differences in lung cancer might vary among people from different backgrounds, and it aims to find ways to personalize prevention and treatment for patients based on their ancestry.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2022 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 5R00CA259223-04 |
| Project ID | NIH-10892072 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include lung cancer patients of diverse ancestral backgrounds, particularly those from Mexican and Colombian populations.
✕Less likely to help
Patients with lung adenocarcinoma who do not have ancestral ties to the populations being studied may not benefit directly from this research.
What this research studies
This research investigates the genetic differences in lung adenocarcinoma among patients from diverse ancestral backgrounds. By analyzing genomic data from over 1,150 lung cancer patients in Mexico and Colombia, as well as a larger dataset from Foundation Medicine, the study aims to uncover how ancestry influences cancer development and progression. The researchers will focus on identifying specific genomic alterations linked to different ancestries, which could lead to tailored prevention and treatment strategies. Patients will be involved in providing clinical data that will help in understanding these disparities.
Why it matters
Potential benefit: If successful, this research could lead to more effective, ancestry-informed treatments for lung adenocarcinoma.
How similar studies have gone: Previous research has shown promising results in understanding cancer disparities through genomic analysis, indicating that this approach could yield valuable insights.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Zhang, Jian — Sloan-Kettering Inst Can Research
- Study coordinator: Zhang, Jian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.