Exploring how air pollution contributes to lung cancer at the molecular level
Investigating the molecular signatures and pathways indicative of air pollution toxicity in lung carcinogenesis using single- and multi-omics analyses of genomics, proteomics, and metabolomics
This study is looking at how air pollution can cause lung cancer by exploring the roles of different molecules in our bodies, and it aims to help identify people who might be at greater risk so we can find better ways to prevent the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10990367 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms by which air pollution leads to lung cancer, focusing on the roles of various biomolecules such as amino acids and proteins. By utilizing advanced techniques in genomics, proteomics, and metabolomics, the study aims to uncover the complex interactions between these molecules and their impact on cancer development. The research will also develop predictive models to identify individuals at higher risk for lung cancer due to air pollution exposure, providing insights that could inform targeted prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been exposed to high levels of air pollution and are at risk for developing lung cancer.
Not a fit: Patients who do not have a history of significant air pollution exposure or existing lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for lung cancer related to air pollution exposure.
How similar studies have performed: Previous research has shown promise in using multi-omics approaches to understand cancer mechanisms, indicating that this study builds on established methodologies.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Tang, Ziyin — Emory University
- Study coordinator: Tang, Ziyin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.