Exploring how a personalized Mediterranean diet can help prevent Alzheimer's dementia through the gut-brain connection.

Who could benefit from this research

What this research studies

This research investigates the relationship between the Mediterranean diet and cognitive health, specifically focusing on Alzheimer's dementia prevention. It aims to personalize dietary recommendations based on individual gut microbiome profiles, as preliminary data suggest that these profiles may influence how well a person responds to the diet. The study will utilize randomized controlled trials to assess the effectiveness of tailored dietary interventions, leveraging existing biological samples for a comprehensive analysis. By understanding the gut-brain axis, the research seeks to identify how dietary changes can impact cognitive function over time.

Why it matters

Where this research is happening

• Brigham and Women's Hospital
  Boston, United States Active

Researchers

• Principal investigator: Wang, Dong — Brigham and Women's Hospital
• Study coordinator: Wang, Dong

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.