Exploring how a new VNS device affects the autonomic nervous system and organ function
VNS Modulation of the Central Autonomic Network and its Effects on ANS
This study is looking at how a new device called Microburst, which helps with nerve stimulation, affects heart health and other body functions in people who have just started using it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10930826 on NIH RePORTER |
What this research studies
This research investigates the effects of a novel VNS device called Microburst on the autonomic nervous system and various peripheral organ systems. Participants who have recently received this device will undergo a series of tests to evaluate how different stimulation frequencies impact their cardiovascular health and other physiological functions. The study includes a washout period where the device is turned off, followed by assessments of multiple organ responses to varying stimulation settings. The goal is to understand the broader implications of VNS on health outcomes.
Who could benefit from this research
Good fit: Ideal candidates are individuals who have recently received the Microburst VNS device and are willing to participate in follow-up assessments.
Not a fit: Patients who do not have the Microburst VNS device or those with contraindications for VNS therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions related to autonomic nervous system dysfunction.
How similar studies have performed: Previous research has shown promising results with VNS therapies, but the specific use of the Microburst device is a novel approach.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Nahas, Ziad — University of Minnesota
- Study coordinator: Nahas, Ziad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.