Exploring how a cannabinoid receptor can reduce inflammation in the breast during breastfeeding.
Investigating the therapeutic potential of CB2 in modulation of inflammation in the mammary gland during lactation
['FUNDING_R15'] · UNIVERSITY OF PUERTO RICO AT AGUADILLA · NIH-10514546
This study is looking at how a specific receptor in the body might help reduce inflammation caused by mastitis, a painful condition some women experience while breastfeeding, to find ways to make breastfeeding easier and more comfortable.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PUERTO RICO AT AGUADILLA (nih funded) |
| Locations | 1 site (AGUADILLA, UNITED STATES) |
| Trial ID | NIH-10514546 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the cannabinoid type 2 (CB2) receptor in reducing inflammation associated with mastitis, a condition that can occur in women during the early weeks of breastfeeding. The study aims to understand how activating this receptor can decrease harmful inflammatory cytokines and reactive oxygen species that damage mammary tissue and affect milk production. By utilizing various agonists that activate CB2, the research seeks to identify potential therapeutic strategies to alleviate inflammation and support breastfeeding.
Who could benefit from this research
Good fit: Ideal candidates for this research are postpartum women experiencing symptoms of mastitis or inflammation in the breast.
Not a fit: Patients who are not postpartum or do not experience mastitis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help women maintain breastfeeding by reducing inflammation and associated complications.
How similar studies have performed: Previous studies have shown promising results regarding the anti-inflammatory effects of CB2 activation in chronic inflammatory conditions, suggesting potential for success in this area.
Where this research is happening
AGUADILLA, UNITED STATES
- UNIVERSITY OF PUERTO RICO AT AGUADILLA — AGUADILLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PEREZ LASPIUR, JULIANA — UNIVERSITY OF PUERTO RICO AT AGUADILLA
- Study coordinator: PEREZ LASPIUR, JULIANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's Disease, Alzheimer disease, Alzheimer syndrome