Exploring heart rhythm disorders using advanced ECG analysis
Novel disease-electrocardiogram associations in inherited arrhythmia syndromes
This study is looking at ways to make heart tests (ECGs) better at spotting inherited heart rhythm problems, especially in kids, by using a big collection of heart readings to create smarter tools for doctors to understand the results more clearly.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kapiolani Medical Center Women/children NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-10684855 on NIH RePORTER |
What this research studies
This research investigates how electrocardiograms (ECGs) can be improved to better diagnose inherited arrhythmia syndromes, which can lead to serious heart issues. By creating a large database of ECG readings from over 27,000 individuals, the researchers aim to develop new algorithms that can interpret ECG results more accurately. This approach seeks to reduce variability in ECG interpretation, making it easier for healthcare providers to identify abnormal heart rhythms in patients, especially children. The study focuses on using Z-scores to standardize ECG readings, enhancing diagnostic precision.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and young adults who are at risk for inherited arrhythmia syndromes.
Not a fit: Patients with non-inherited arrhythmia conditions or those who do not undergo ECG testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable diagnoses of heart rhythm disorders in patients, potentially preventing serious health complications.
How similar studies have performed: Previous research has shown promise in using advanced algorithms and large datasets to improve ECG interpretation, suggesting that this approach could yield significant advancements.
Where this research is happening
Honolulu, United States
- Kapiolani Medical Center Women/children — Honolulu, United States (Active)
Researchers
- Principal investigator: Bratincsak, Andras — Kapiolani Medical Center Women/children
- Study coordinator: Bratincsak, Andras
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.