Exploring hearing loss in individuals with Down syndrome
Multidimensional investigation of auditory dysfunction in Down syndrome
This study is looking at how hearing problems affect people with Down syndrome, aiming to understand why these issues happen and how they can improve the lives of those with the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11083702 on NIH RePORTER |
What this research studies
This research investigates the widespread auditory dysfunction experienced by individuals with Down syndrome, focusing on understanding the mechanisms behind hearing loss associated with an extra copy of chromosome 21. The study will involve a detailed assessment of auditory and vestibular functions in a cohort of 300 participants using various tests, including audiometry and auditory brainstem response testing. By gathering comprehensive health histories and evaluating co-occurring conditions, the research aims to uncover critical insights that could enhance the quality of life for those affected.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Down syndrome who may be experiencing hearing loss or related auditory dysfunction.
Not a fit: Patients without Down syndrome or those who do not exhibit any auditory dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of hearing loss in individuals with Down syndrome, enhancing their overall development and quality of life.
How similar studies have performed: Previous research has shown that understanding auditory dysfunction in genetic conditions can lead to significant advancements in treatment and support, suggesting a promising avenue for this investigation.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.