Exploring health restoration through multiple interventions for cognitive decline
Official title: Network models to capture multiple outcomes resulting from multi-component, salutogenic interventions
Funded at Oregon Health & Science University · NIH-10898728 · Data updated 2026-11-12
This study is looking at how exercise and a plant extract might help older adults improve their thinking and memory skills, using mice to see what works best for keeping our brains healthy as we age.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | August 4, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $155,547 |
| NIH project number | 5K08AT012477-02 |
| Project ID | NIH-10898728 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing cognitive decline or those interested in preventive measures against age-related cognitive issues.
✕Less likely to help
Patients with severe cognitive impairment or those who are not able to engage in physical activity may not benefit from this research.
What this research studies
This research investigates how various interventions can help restore cognitive function in aging individuals. Using a mouse model, the study will evaluate the effects of exercise and a botanical extract on cognitive health. By analyzing molecular and functional changes, the research aims to identify effective strategies for improving resilience against cognitive decline. The findings could provide insights into non-pharmaceutical approaches to enhance overall health and cognitive performance.
Why it matters
Potential benefit: If successful, this research could lead to new non-drug interventions that improve cognitive health in aging populations.
How similar studies have gone: Previous research has shown promising results with similar interventions, indicating potential for success in this approach.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Chamberlin, Steven — Oregon Health & Science University
- Study coordinator: Chamberlin, Steven
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.