Exploring health restoration through multiple interventions for cognitive decline

Network models to capture multiple outcomes resulting from multi-component, salutogenic interventions

NIH-funded research Oregon Health & Science University · NIH-10898728

This study is looking at how exercise and a plant extract might help older adults improve their thinking and memory skills, using mice to see what works best for keeping our brains healthy as we age.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-10898728 on NIH RePORTER

What this research studies

This research investigates how various interventions can help restore cognitive function in aging individuals. Using a mouse model, the study will evaluate the effects of exercise and a botanical extract on cognitive health. By analyzing molecular and functional changes, the research aims to identify effective strategies for improving resilience against cognitive decline. The findings could provide insights into non-pharmaceutical approaches to enhance overall health and cognitive performance.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or those interested in preventive measures against age-related cognitive issues.

Not a fit: Patients with severe cognitive impairment or those who are not able to engage in physical activity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new non-drug interventions that improve cognitive health in aging populations.

How similar studies have performed: Previous research has shown promising results with similar interventions, indicating potential for success in this approach.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.