Exploring gut bacteria that help regulate fat metabolism and ceramide levels
Investigating Metabolically Protective Members of the Microbiota that Modulate Ceramides
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF UTAH · NIH-10862789
This study is looking at how certain gut bacteria can help manage weight and blood sugar levels, especially for people dealing with obesity and type 2 diabetes, by finding out which bacteria can protect against the effects of high-fat diets.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10862789 on ClinicalTrials.gov |
What this research studies
This research investigates the role of gut bacteria in managing metabolism, particularly focusing on how certain bacteria can influence the production of ceramides, which are linked to metabolic diseases like obesity and type 2 diabetes. The study aims to identify specific bacterial communities that provide metabolic protection against high-fat diets by reducing weight gain and improving glucose levels. By understanding the relationship between these bacteria and ceramide production, the research seeks to uncover new insights into how gut microbiota can be leveraged to improve metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for or currently experiencing metabolic disorders such as obesity or type 2 diabetes.
Not a fit: Patients who do not have metabolic disorders or those with conditions unrelated to metabolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating metabolic diseases by harnessing the beneficial effects of specific gut bacteria.
How similar studies have performed: Previous studies have shown promising results regarding the relationship between gut microbiota and metabolic health, indicating that this research builds on established findings.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KLAG, KENDRA ALYSE — UNIVERSITY OF UTAH
- Study coordinator: KLAG, KENDRA ALYSE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus