Exploring gut bacteria and metabolites to find new types of Irritable Bowel Syndrome
A Systems Biology Approach Using Fecal Microbiota and Metabolomics to Identify Novel Subtypes in Irritable Bowel Syndrome
This study is looking at how the bacteria in your gut and their byproducts can help us understand the different types of Irritable Bowel Syndrome (IBS) and find better ways to treat it, so if you have IBS, your participation could help improve your care!
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10848525 on NIH RePORTER |
What this research studies
This research investigates how the interactions between gut bacteria and metabolites can help identify different subtypes of Irritable Bowel Syndrome (IBS). By analyzing fecal samples and using advanced statistical methods, the study aims to uncover biological responses to various treatments. Patients may provide samples and participate in assessments that could lead to more personalized and effective management of their IBS symptoms. The research is led by Dr. Allen Lee, a gastroenterologist focused on improving care for IBS patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Irritable Bowel Syndrome, particularly those experiencing diarrhea-predominant symptoms.
Not a fit: Patients with other gastrointestinal disorders or those not diagnosed with Irritable Bowel Syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more tailored treatments for patients with Irritable Bowel Syndrome, improving their quality of life.
How similar studies have performed: Previous research has shown promise in using microbiota analysis to inform treatment strategies for gastrointestinal disorders, indicating potential success for this approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Lee, Allen a — University of Michigan at Ann Arbor
- Study coordinator: Lee, Allen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.