Exploring genetic variations linked to schizophrenia
Official title: An Investigation of Tandem Repeat Variation in Schizophrenia
Funded at Icahn School of Medicine at Mount Sinai · NIH-10951937 · Data updated 2026-11-12
This study is looking at how certain genetic changes might be linked to schizophrenia, and it’s for people with the condition who want to help researchers understand more about what causes it and how to improve treatments.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 15, 2024 |
| Project end | May 14, 2026 |
| Funding year | 2024 |
| Award (this year) | $464,750 |
| NIH project number | 1R21MH137536-01 |
| Project ID | NIH-10951937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with schizophrenia who are willing to participate in genetic analysis.
✕Less likely to help
Patients without a diagnosis of schizophrenia or those who do not wish to undergo genetic testing may not benefit from this research.
What this research studies
This research investigates the role of tandem repeat variations in the genetic makeup of individuals with schizophrenia. By utilizing advanced profiling tools and analyzing large-scale genomic data, the study aims to identify specific genetic factors that may contribute to the risk of developing schizophrenia. Patients with schizophrenia may have their genetic information analyzed to uncover potential links between these variations and their condition, which could enhance understanding and treatment options. The approach combines innovative algorithms with comprehensive genetic data to provide insights into this complex mental health disorder.
Why it matters
Potential benefit: If successful, this research could lead to the identification of new genetic risk factors for schizophrenia, potentially improving diagnosis and treatment strategies.
How similar studies have gone: While the investigation of tandem repeats in schizophrenia is relatively novel, similar approaches in other neurological disorders have shown promising results.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Birnbaum, Rebecca — Icahn School of Medicine at Mount Sinai
- Study coordinator: Birnbaum, Rebecca
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.