Exploring genetic factors to develop new treatments for Alzheimer's disease
Translating Genetic Risk Factors to Therapies: From Big Data to Druggable Targets
This study is looking at how certain genes related to Alzheimer's disease can help create new treatments, so that patients like you might have better options that fit your unique genetic makeup.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10862813 on NIH RePORTER |
What this research studies
This research investigates how genetic variations linked to Alzheimer's disease can inform the development of new therapies. By analyzing genetic data from patients, the study aims to identify druggable targets that could lead to innovative treatment options. The research will utilize advanced techniques such as single-cell sequencing and patient samples to understand the role of specific genes in disease progression. Patients may benefit from the insights gained, which could lead to more effective therapies tailored to their genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk due to genetic factors.
Not a fit: Patients with Alzheimer's disease not associated with the genetic factors being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted therapies for Alzheimer's disease that improve patient outcomes.
How similar studies have performed: Previous research has shown promise in using genetic insights to develop treatments for complex diseases, indicating a potential for success in this approach.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Shaw, Benjamin C. — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Shaw, Benjamin C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.