Exploring genetic factors of Alzheimer's disease in diverse ancestry groups
Project 1: Genetic Discovery Within Diverse Ancestry Cohorts
This study is looking at how genetics might affect the risk of developing Alzheimer's disease in African American, African, and Hispanic/Latinx communities, hoping to find unique genetic clues that could help us understand why some people are more at risk than others.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10892913 on NIH RePORTER |
What this research studies
This research investigates how genetic factors associated with Alzheimer's disease vary among African American, African, and Hispanic/Latinx populations. By analyzing genetic data from these diverse groups, the project aims to identify unique genetic variants that may influence the risk of developing Alzheimer's. The researchers will employ advanced statistical methods to uncover regulatory elements and analyze the genetic makeup of these populations, ultimately aiming to understand the molecular mechanisms behind Alzheimer's risk. This work seeks to enhance our understanding of how ancestry affects Alzheimer's disease susceptibility.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from African American, African, and Hispanic/Latinx backgrounds who are at risk for Alzheimer's disease.
Not a fit: Patients who do not belong to the targeted ancestry groups may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized prevention and treatment strategies for Alzheimer's disease tailored to specific ancestry groups.
How similar studies have performed: Previous research has shown that understanding genetic diversity can lead to significant advancements in identifying risk factors for diseases like Alzheimer's, indicating a promising approach.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Bush, William S — University of Miami School of Medicine
- Study coordinator: Bush, William S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.