Exploring genetic factors in childhood behavioral disorders
Official title: Understanding developmental neurogenomic mechanisms in externalizing disorders
Funded at Massachusetts General Hospital · NIH-10993148 · Data updated 2026-11-12
This study is looking at how our genes might play a role in conditions like ADHD that kids and teens often face, and it aims to help us understand these disorders better so we can find new ways to treat them.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $195,859 |
| NIH project number | 5K08MH135343-02 |
| Project ID | NIH-10993148 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents aged 12 to 20 who exhibit symptoms of externalizing disorders like ADHD.
✕Less likely to help
Patients outside the age range of 12 to 20 or those without externalizing disorders may not benefit from this research.
What this research studies
This research investigates the genetic mechanisms behind externalizing disorders, such as ADHD, that often emerge during childhood and adolescence. By analyzing genetic data and brain structure, the study aims to uncover how specific genes influence the development of these disorders. The principal investigator, Dr. Travis Mallard, will utilize advanced bioinformatics techniques to identify genetic links and their effects on brain development. This research could lead to a better understanding of how these disorders develop and potentially inform future treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment strategies for children with externalizing disorders.
How similar studies have gone: Previous research has shown promising results in understanding genetic influences on behavioral disorders, indicating that this approach has potential for success.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Mallard, Travis T — Massachusetts General Hospital
- Study coordinator: Mallard, Travis T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.