Exploring genetic factors and neuroimaging techniques to understand Alzheimer's Disease
Genetics of deep-learning-derived neuroimaging endophenotypes for Alzheimer's Disease
['FUNDING_U01'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-10885136
This study is looking at how our genes and brain scans can help us understand Alzheimer's Disease better, with the hope of finding new ways to diagnose and treat people living with it.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10885136 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic underpinnings of Alzheimer's Disease (AD) by utilizing advanced neuroimaging techniques and deep learning methods. It aims to analyze large-scale neuroimaging data to identify new biomarkers associated with AD, which could enhance our understanding of the disease's biology. By integrating whole genome sequencing with neuroimaging data, the study seeks to uncover novel genetic factors that contribute to the development and progression of Alzheimer's. This approach may lead to improved diagnostic tools and therapeutic strategies for patients affected by AD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are experiencing cognitive decline or have a diagnosis of Alzheimer's Disease.
Not a fit: Patients under the age of 65 or those without cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the identification of new biomarkers for Alzheimer's Disease, potentially improving early diagnosis and treatment options for patients.
How similar studies have performed: Previous research has shown promise in using advanced neuroimaging and genetic analysis to identify biomarkers for Alzheimer's, indicating that this approach has potential for success.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHI, DEGUI — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: ZHI, DEGUI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.