Exploring genetic differences in heart, lung, blood, and sleep disorders among diverse populations
Investigating ancestry-specific genetic variation associated with HLBS phenotypes in diverse patient biobanks
This study is looking at how certain genes that are more common in African American individuals can affect heart, lung, blood, and sleep problems, with the goal of finding better ways to treat these issues and improve health for Black adults.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11031319 on NIH RePORTER |
What this research studies
This research investigates how genetic variations specific to African American individuals influence heart, lung, blood, and sleep disorders. By utilizing a large biobank that includes diverse patient data, the study aims to identify ancestry-specific genetic markers that could lead to better understanding and treatment of these conditions. The approach focuses on addressing the significant health disparities faced by Black adults, who experience higher mortality rates from cardiovascular diseases. Participants will contribute their genetic information and health records to help uncover these critical insights.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals aged 21 and older who are willing to share their genetic and health information.
Not a fit: Patients who do not identify as African American or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for heart, lung, blood, and sleep disorders in African American populations.
How similar studies have performed: Previous research has shown that focusing on diverse genetic backgrounds can lead to significant advancements in understanding and treating health disparities, making this approach promising.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Zhang, David — University of Pennsylvania
- Study coordinator: Zhang, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.