NIH-funded research Career grant

Exploring genetic and social factors in substance use disorders

Official title: Using novel data sources across genetic, biological, and social domains to refine genome-wide investigations of substance use disorders

Funded at Yale University · NIH-10985085 · Data updated 2026-11-12

This study is looking at how our genes and social factors can influence substance use problems, especially for people who might not have been diagnosed yet, to help find better ways to understand and support those dealing with these challenges.

More Substance Use Disorders research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startAugust 1, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$181,040
NIH project number1K01DA058807-01A1
Project IDNIH-10985085 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with a history of substance use or those who have experienced substance use disorders.

Less likely to help

Patients who have never used substances or do not have any history of substance use disorders may not benefit from this research.

What this research studies

This research investigates the genetic and social influences on substance use disorders (SUDs) by utilizing advanced data sources. It aims to improve the understanding of how different substances interact and affect individuals, particularly focusing on those who may not have a formal diagnosis. By analyzing electronic health records and toxicology data, the research seeks to identify genetic predispositions and better define the characteristics of individuals affected by SUDs. This comprehensive approach could lead to more accurate diagnoses and targeted interventions for those struggling with substance use.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods and personalized treatment strategies for individuals with substance use disorders.

How similar studies have gone: Previous research has shown promise in using genetic and electronic health record data to understand substance use disorders, indicating that this approach could yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Deak, Joseph D. — Yale University
  • Study coordinator: Deak, Joseph D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.