Exploring genetic and immune differences in colorectal cancer among Latino populations
Investigation of within-Latino heterogeneity in colorectal cancer mutational and T cell profiles
This study is looking at how genetics and immune responses to colorectal cancer can vary among different Latino communities in the U.S., and it aims to understand why some groups may face higher risks, so if you're a Latino patient, your participation could help improve health outcomes for your community.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11080654 on NIH RePORTER |
What this research studies
This research investigates the differences in genetic and immune responses to colorectal cancer (CRC) within various Latino communities in the U.S. By analyzing data and biospecimens from the Latino Colorectal Cancer Consortium, the study aims to understand how factors like ethnicity and genetic ancestry affect CRC outcomes. The research focuses on addressing health disparities that exist among Latino groups, particularly in relation to CRC mortality rates. Patients may be involved in providing biospecimens and health information to help uncover these critical insights.
Who could benefit from this research
Good fit: Ideal candidates for this research include Latino individuals diagnosed with colorectal cancer, particularly those from diverse backgrounds such as Puerto Rican, Cuban, and Mexican communities.
Not a fit: Patients who do not identify as Latino or those without a diagnosis of colorectal cancer may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and health equity for Latino patients with colorectal cancer.
How similar studies have performed: Previous research has shown that addressing health disparities in minority populations can lead to significant advancements in understanding and treating diseases, making this approach both relevant and promising.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Schmit, Stephanie L. — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Schmit, Stephanie L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.