Exploring gene mutations linked to skin conditions in Latinx patients
Investigation of Filaggrin Gene Mutations among Latinx patients with Atopic Dermatitis
This study is looking at how certain gene changes might affect the severity of atopic dermatitis in Latinx patients, with the hope of improving how we diagnose and manage this skin condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10909292 on NIH RePORTER |
What this research studies
This research investigates the role of specific gene mutations in the development of atopic dermatitis among Latinx patients. By examining the filaggrin gene, which is known to affect skin barrier function, the study aims to understand how genetic variations and ancestry contribute to the severity of this chronic skin condition. The research will involve collecting genetic data from participants and analyzing how these factors interact with environmental influences. Ultimately, the goal is to enhance diagnostic and management strategies for atopic dermatitis in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latinx individuals diagnosed with atopic dermatitis, particularly those experiencing severe symptoms.
Not a fit: Patients who do not have atopic dermatitis or those from non-Latinx backgrounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for atopic dermatitis in Latinx patients.
How similar studies have performed: Previous research has shown promising results in understanding genetic factors in atopic dermatitis, but this specific focus on Latinx populations is relatively novel.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Chiesa Fuxench, Zelma Charlotte — University of Pennsylvania
- Study coordinator: Chiesa Fuxench, Zelma Charlotte
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.