Exploring gene activity in human and mouse brains using advanced imaging techniques
Multi-modal spatial genomics in the mouse and human brains
This study is exploring new ways to see and understand how genes are arranged in the brains of humans and mice, which could help us learn more about how brain cells work together and communicate, ultimately helping us uncover the mysteries of brain function.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Spatial Genomics, INC. NIH-funded |
| Lab location | 1 site (Pasadena, UNITED STATES) |
| Project ID | NIH-10867435 on NIH RePORTER |
What this research studies
This research focuses on developing innovative tools to visualize and analyze the spatial organization of genes in human and mouse brain samples. By utilizing a technology called sequential fluorescence in situ hybridization (seqFISH), the project aims to image thousands of genes simultaneously, providing insights into the cellular structure and interactions within the brain. This approach could help identify new cell types and understand how neurons communicate with each other and with glial cells, which is crucial for unraveling the complexities of brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions or those interested in the genetic basis of brain function.
Not a fit: Patients with conditions unrelated to brain function or those not willing to participate in research may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain disorders and developing targeted therapies.
How similar studies have performed: Previous research using similar spatial genomics techniques has shown promising results in understanding brain structure and function.
Where this research is happening
Pasadena, UNITED STATES
- Spatial Genomics, INC. — Pasadena, United States (Active)
Researchers
- Principal investigator: Frieda, Kirsten — Spatial Genomics, INC.
- Study coordinator: Frieda, Kirsten
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.