Exploring estuarine sediments for new natural products that may help treat diseases
Official title: Integrated metabolomic and microbial community analysis of estuarine sediments and their potential as sources of bioactive natural products
Funded at Oregon State University · NIH-11111154 · Data updated 2026-11-12
This study is looking at tiny living things in mud from estuaries to find new natural medicines that could help treat tough infections and long-lasting illnesses, which could be great news for patients needing better treatments.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project start | June 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $12,068 |
| NIH project number | 5F31AT012840-02 |
| Project ID | NIH-11111154 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from infections or chronic diseases that are resistant to current treatments.
✕Less likely to help
Patients with conditions that do not involve drug resistance or chronic diseases may not benefit from this research.
What this research studies
This research investigates the diverse microbial communities found in estuarine sediments, particularly focusing on their potential to produce new bioactive compounds. By analyzing these sediments, researchers aim to identify metabolites that could lead to the development of new pharmaceuticals, especially to combat drug-resistant infections and chronic diseases. The study employs advanced techniques like 16S gene sequencing to understand the microbial composition and its relationship to the production of these compounds. Patients may benefit from the discovery of novel treatments derived from these natural products.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments for drug-resistant infections and chronic diseases.
How similar studies have gone: Other research has shown promise in discovering new pharmaceuticals from microbial communities, indicating that this approach has potential for success.
Where this research is happening
-
Oregon State University
Corvallis, United States Active
Researchers
- Principal investigator: Redick, Margaret — Oregon State University
- Study coordinator: Redick, Margaret
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.