Exploring detailed brain connectivity using advanced MRI techniques

Unlocking whole brain, layer-specific functional connectivity with 3D VAPER fMRI

['FUNDING_R03'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-10814251

This study is looking at how different layers of the brain work together using advanced imaging technology, and it's for both healthy people and those with neurological conditions to help us learn more about brain function.

Quick facts

Phase['FUNDING_R03']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded)
Locations1 site (CHAMPAIGN, UNITED STATES)
Trial IDNIH-10814251 on ClinicalTrials.gov

What this research studies

This research focuses on using ultra-high field fMRI technology to investigate the functional connectivity of different layers within the human brain. By achieving high-resolution imaging, the study aims to enhance our understanding of brain micro-circuitry in both healthy individuals and those with neurological conditions. The approach involves developing a new imaging sequence that provides accurate and sensitive measurements of brain activity across the entire brain, overcoming previous limitations in spatial coverage and specificity. Patients may undergo non-invasive imaging to help researchers gather data on brain function.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals with neurological conditions or healthy volunteers interested in contributing to brain research.

Not a fit: Patients with contraindications for MRI, such as those with certain implants or severe claustrophobia, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for various neurological disorders.

How similar studies have performed: While the approach is innovative, similar studies using advanced imaging techniques have shown promise in enhancing our understanding of brain function.

Where this research is happening

CHAMPAIGN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Disorder, Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.