Exploring decision-making for breast cancer prevention in diverse women at high risk
Integrating Breast Cancer and Cardiovascular Disease Risk to Explore Decision-Making for Chemoprevention Among Racially/Ethnically Diverse Women at High Risk for Breast Cancer
This study is looking at why women from diverse backgrounds who are at high risk for breast cancer are less likely to use certain preventive medications for breast cancer, even though they often take other medications for heart health, and it aims to find ways to help them feel more comfortable discussing these options with their doctors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10944132 on NIH RePORTER |
What this research studies
This research investigates the decision-making processes of racially and ethnically diverse women who are at high risk for breast cancer, particularly those with high-risk breast lesions. It aims to understand why these women are less likely to use chemoprevention methods, such as selective estrogen receptor modulators and aromatase inhibitors, compared to their uptake of statins for cardiovascular disease prevention. By employing a human-centered design approach, the study will identify barriers and facilitators in the patient journey from risk awareness to medication discussions with healthcare providers. The goal is to improve the uptake of breast cancer chemoprevention among these high-risk populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are racially and ethnically diverse women with high-risk breast lesions, such as atypical hyperplasia or lobular carcinoma in situ.
Not a fit: Patients who do not have high-risk breast lesions or those who are not racially or ethnically diverse may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to increased use of effective breast cancer prevention strategies among high-risk women, potentially reducing breast cancer incidence.
How similar studies have performed: While there have been numerous studies on breast cancer chemoprevention, this research is novel in its focus on the intersection of breast cancer and cardiovascular disease prevention decision-making.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Kukafka, Rita — Columbia University Health Sciences
- Study coordinator: Kukafka, Rita
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.