NIH-funded research Career grant

Exploring community factors affecting opioid use disorder and treatment adherence

Official title: Understanding the role of community determinants in opioid use disorder and program implementation factors influencing patient adherence to opioid agonist therapy

Funded at Geisinger Clinic · NIH-10864937 · Data updated 2026-11-12

This study is looking at how different community and program factors affect the risk of opioid use disorder and how well medication-assisted treatment works, with the goal of finding ways to help people stick with their treatment and improve their recovery.

More Opioid Use research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionGeisinger Clinic
NIH-funded
Lab location1 site (Danville, United States)
Project startJuly 1, 2020
Project endDecember 31, 2025
Funding year2024
Award (this year)$162,032
NIH project number5K01DA049903-05
Project IDNIH-10864937 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals aged 21 and older who are receiving or are eligible for medication-assisted treatment for opioid use disorder.

Less likely to help

Patients who are not currently engaged in treatment for opioid use disorder or those under 21 years old may not benefit from this research.

What this research studies

This research investigates how various community and program factors influence the risk of opioid use disorder (OUD) and the effectiveness of medication-assisted treatment (MAT). It aims to identify barriers to long-term treatment adherence and develop strategies to enhance patient retention in MAT programs. The project will utilize electronic health record data to conduct a two-phase epidemiologic study, providing insights that could improve treatment outcomes for individuals struggling with OUD. The research is supported by a team of experienced mentors and aims to equip the principal investigator with the skills needed for independent research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment adherence for patients with opioid use disorder, ultimately enhancing their recovery outcomes.

How similar studies have gone: Previous research has shown success in using community and programmatic factors to improve treatment adherence in similar populations, indicating that this approach has potential.

Where this research is happening

  • Geisinger Clinic
    Danville, United States
    Active

Researchers

  • Principal investigator: Poulsen, Melissa — Geisinger Clinic
  • Study coordinator: Poulsen, Melissa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.